Final stages in escort aptamer planning include synthetic variations of one’s truncated aptamer
Final stages in escort aptamer planning include synthetic variations of one’s truncated aptamer Further nuclease stabilization is achieved by substitution of 2?-OCHstep three for 2?-OH at purine positions. As the 2?-OCH3 moiety is not compatible with current SELEX process enzymes, this alteration must occur during chemical synthesis following evolution of
